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Clinical Trials: Clinical Trial Model
clinical trials

LICR believes that clinical research in cancer cannot be undertaken as simply product development, but rather requires a systematic, academic approach to develop rational therapeutic strategies in the only setting that really counts – the cancer patient. LICR is one of very few academic organizations, anywhere in the world, that produces its own regulatory-standard therapeutic study agents, and plans, conducts, administers, and sponsors its own clinical trials. This model allows basic investigations to continue into early stage clinical evaluation of a new therapy, making the clinic an essential arm of the research enterprise.

LICR is currently exploring three separate cancer treatment modalities: cancer vaccines and targeted antibodies. These targeted therapies are designed to prevent the growth of tumours and the spread of cancer, without the dangerous and unpleasant side effects of current cancer therapies.

 

Targeted Antibodies

LICR has focused on tumour immunology as one of its major research efforts for more than three decades. Over the years, LICR investigators have assembled a large portfolio of mouse monoclonal antibodies (mAbs) which specifically target tumors from a wide-range of cancers. A targeted antibody can be used to trigger the immune system to attack cancer cells, or can be used to deliver a toxin or radioactive molecule direct to the cancer cell.

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Cancer Vaccines

LICR is a leading authority in the development and testing of therapeutic cancer vaccines. The concept of using cancer vaccines to modulate human cancer is based upon the body’s ability to induce immune responses specific for antigens expressed specifically, or preferentially, by tumor cells. A vaccine would thus stimulate the body’s own immune system to fight cancer cells, and prevent their spread around the body.

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Clinical Trials Links
icon Overview
icon Targeted Antibodies
icon Cancer Vaccines

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Patient Resources
icon Victorian Cancer Agency
icon Cancer Council of Victoria
icon Cancer Trials Australia
icon Clinical Trials (USA)
icon Cancer Net (USA)
icon Cancer.gov (USA)
icon CancerBACUP (UK)
icon Joint Oncology Unit
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Current Clinical Trials

Study of NY-ESO-1 ISCOMATRIX® in Patients with High-Risk, Resected Melanoma

Biodistribution Study of CMD-193 in Patients with Advanced Tumours Expressing the Lewis-Y Antigen

Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer

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