PPT Slide

Step 1: Screening of Compound Libraries

Wet Screen

HTS: 10,000 –100,000 comp/day

uHTS: > 100,000 comp/day

Hit Rate: 1 in 100,000 (non-focused libs)

Virtual Screen

5-20min per compound per CPU

i.e. approx 10,000 comp/day

(64 CPU cluster, structure-based

Docking/screening)