PPT Slide

S

GRB2

OSM

JAK1

Y

Y

Y

Y

JAK1

P

P

P

P

P

P

STAT3

Nucleus

Cytoplasm

Transcription

Factors

SHC

SOS

RAS

RAF

MEK

MAPK

?

P

P

P

Cell Membrane

OSM Signalling

OSMRb

or

LIFRb

gp130

STAT3

STAT3

Transcription

(ERK1/2)

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