Epithelial lab front page

Lab head

Current Research

Laboratory staff

Selected Publications

New Stuff

Epithelial Biochemistry Laboratory Melanie Condron BSc(Hons) Research Officer

Current work: Analysis of the APC tumour suppressor gene product

Research Interests: Gene structure and function

Publication Snapshot:
Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cells.
Agrotis A, Condron M, Bobik A.
FEBS Lett. 467: 128-132 (2000). [Medline entry]

Distinct patterns of transforming growth factor-beta isoform and receptor expression in human atherosclerotic lesions. Colocalization implicates TGF-beta in fibrofatty lesion development.
Bobik A, Agrotis A, Kanellakis P, Dilley R, Krushinsky A, Smirnov V, Tararak E, Condron M, Kostolias G.
Circulation. 99: 2883-2891 (1999). [Medline entry]

The genes encoding mammalian chaperonin 60 and chaperonin 10 are linked head-to-head and share a bidirectional promoter.
Ryan MT, Herd SM, Sberna G, Samuel MM*, Hoogenraad NJ, Hoj PB.
Gene. 196:9-17 (1997). [Medline entry]
* Melanie under her maiden name