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Epithelial Biochemistry Laboratory Sabine Kleikamp Dipl Biol PhD student

Current work: EphA3 signal transduction pathways and function in normal and oncogenic development

Thesis topic: EphA3 signalling in normal and oncogenic development

Supervisor: Martin Lackmann

[To student pages]

Publication Snapshot:
The role of the Eph-ephrin signalling system in the regulation of developmental patterning.
Coulthard MG, Duffy S, Down M, Evans B, Power M, Smith F, Stylianou C, Kleikamp S, Oates A, Lackmann M, Burns GF, Boyd AW.
Int J Dev Biol. 46: 375-384 (2002). [Medline entry]

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling.
Lawrenson ID, Wimmer-Kleikamp SH, Lock P, Schoenwaelder SM, Down M, Boyd AW, Alewood PF, Lackmann M.
J Cell Sci. 115: 1059-1072 (2002). [Medline entry]