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Citation |
| 1. | Simpson, R.J. and Nice, E.C. (1984) In situ cyanogen bromide cleavage of N-terminally blocked proteins in a gas-phase sequencer. Biochem. Int. 8:787-791. |
| 2. | van Driel, I.R., Stearne, P.A., Grego, B., Simpson, R.J. and Goding, J.W. (1984) The receptor for transferrin on murine myeloma cells: One-step purification based on its physiology and partial amino acid sequence. J. Immunol. 133:3220-3224. |
| 3. | Stearne, P.A., van Driel, I.R., Grego, B., Simpson, R.J. and Goding, J.W. (1985) The murine plasma cell antigen PC-1: Purification and partial amino acid sequence. J. Immunol. 134:443-448. |
| 4. | Grego, B., van Driel, I.R., Stearne, P.A., Goding, J.W., Nice, E.C. and Simpson, R.J. (1985) A microbore high performance liquid chromatography strategy for the purification of polypeptides for gas-phase sequence analysis: Structural studies on the murine transferrin receptor. Eur. J. Biochem. 148:485-491. |
| 5. | Grego, B., van Driel, I.R., Goding, J.W., Nice, E.C. and Simpson, R.J. (1986) Use of microbore high-performance liquid chromatography for purifying subnanomole levels of polypeptides for microsequencing: Structural studies on the murine plasma cell antigen PC-1. Int. J. Peptide Protein Res. 27:201-207. |
| 6. | Nice, E.C., Grego, B. and Simpson, R.J. (1985) Application of short microbore HPLC 'guard' columns for the preparation of samples for protein microsequencing. Biochem. Int. 11:187-195. |
| 7. | Burgess, A.W., Metcalf, D., Kozka, I.J., Simpson, R.J., Vairo, G., Hamilton, J.A. and Nice, E.C. (1985) Purification of two forms of colony-stimulating factor from mouse L-cell conditioned medium. J. Biol. Chem. 260:16004-16011. |
| 8. | Masakuni, M., Simpson, R.J. and Isaacs, N.W. (1981) Preliminary x-ray diffraction studies on the "goose-type" lysozyme from the egg white of the black swan Cygnus atratus. Boei Ika Daigakko Zasshi 6(3):168-174. |
| 9. | Simpson, R.J., Smith, J.A., Moritz, R.L., O'Hare, M.J., Rudland, P.S., Morrison, J.R., Lloyd, C.J., Grego, B., Burgess, A.W. and Nice, E.C. (1985) Rat epidermal growth factor: Complete amino acid sequence. Homology with the corresponding murine and human proteins; Isolation of a form truncated at both ends with full in vitro biological activity. Eur. J. Biochem. 153:629-637. |
| 10. | Anderson, M.A., Cornish, E.C., Mau, S-L., Hoggart, R., Atkinson, A., Bonig, I., Williams, E.G., Grego, B., Simpson, R.J., Roche, P., Haley, J., Penschow, J., Niall, H., Tregear, G., Crawford, R., Coghlan, J. and Clarke, A.E. (1985) Molecular cloning of cDNA for a stylar glycoprotein associated with expression of self-incompatibility in Nicotiana alata. In: Plant Cell/Cell Interactions, Current Communications in Molecular Biology (I. Sussex, A. Ellingboe, M. Crouch, and R. Malmberg, eds.). Cold Spring Harbor Laboratory, New York, pp.25-29. |
| 11. | Simpson, R.J., Grego, B., Rubira, M.R., Sparrow, L.G. and Nice, E.C. (1987) Use of short microbore HPLC columns for the concentration, separation and recovery of subnanomole amounts of protein and polypeptides for microsequence analysis. In: Proteins, Structure and Function. (J.J. L'Italien, ed.). Plenum Press, New York, pp.5-20. |
| 12. | Nice, E.C., Smith, J.A., Moritz, R.L., O'Hare, M.J., Rudland, P.S., Morrison, J.R., Lloyd, C.J., Grego, B., Burgess, A.W. and Simpson, R.J. (1987) Complete amino acid sequence determination of rat epidermal growth factor: Characterisation of a truncated form with full in vitro biological activity. In: Proteins, Structure and Function (J.J. L'Italien, ed.). Plenum Press, New York. pp.37-44. |
| 13. | Mau, S.L., Williams, E.G., Atkinson, A., Anderson, M.A., Cornish, E.C., Grego, B., Simpson, R.J., Khey-Pour, A. and Clarke, A.E. (1986) Style proteins of a wild tomato (Lycoperiscon perurianum) associated with expression of self-incompatibility. Planta 169:184-191. |
| 14. | Burgess, A.W., Metcalf, D., Sparrow, L.G., Simpson, R.J. and Nice, E.C. (1986) Granulocyte macrophage colony-stimulating factor from mouse lung conditioned medium. Purification of multiple forms and radioiodination. Biochem. J. 235:805-814. |
| 15. | Simpson, R.J., Moritz, R.L., Nice, E.C., Grego, B., Yoshizaki, F., Sugimura, Y., Freeman, H.C. and Murata, M. (1986) Complete amino acid sequence of a plastocyanin from a green alga, Enteromorpha prolifera. Eur. J. Biochem. 157:497-506. |
| 16. | Grego, B., Nice, E.C. and Simpson, R.J. (1986) Use of a scanning diode-array detector with reversed-phase microbore columns for the real-time spectral analysis of aromatic amino acids in peptides and proteins at the sub-microgram level. Applications to peptide and protein microsequencing. J. Chromatogr. 352:359-368. |
| 17. | Anderson, M.A., Cornish, E.C., Mau, S-L, Williams E.G., Hoggart, R., Atkinson, A., Bonig, I., Grego, B., Simpson, R.J., Roche, P.J., Haley, J., Penschow, J., Niall, H.D., Tregear, G., Coghlan, J., Crawford, R. and Clarke, A.E. (1986) Cloning of cDNA for a stylar glycoprotein associated with expression of self-incompatibility in Nicotiana alata. Nature 321: 38-44. |
| 18. | Jeltsch, J.M., Krozowski, Z., Quirin-Stricker, C., Gronemeyer, H., Simpson, R.J., Garnier, J.M., Krust, A., Jacob, F. and Chambon, P. (1986) Cloning of the chicken progesterone receptor. Proc. Natl. Acad. Sci. USA 83: 5424-5428. |
| 19. | Burgess, A.W., Begley, C.G., Johnson, G.R., Lopez, A.F., Williamson, D.J., Mermod, J.J., Simpson, R.J., Schmitz, A. and DeLamarter, J.F. (1987) Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor. Blood 69: 43-51. |
| 20. | Stewart, G.A. Simpson, R.J., Thomas, W.R. and Turner, K.J. (1987) The physicochemical characterization of a major protein allergen from the house dust mite. Int. Arch. Allergy Appl. Immunol. 82: 444-446. |
| 21. | Van Snick, J., Cayphas, S., Vink, A., Uyttenhove, C., Coulie, P.G., Rubira, M.R. and Simpson, R.J. (1986) Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc. Natl. Acad. Sci. USA 83: 9679-9683. |
| 22. | Simpson, R.J. and Nice, E.C. (1987) The role of microbore HPLC in the purification of subnanomole amounts of polypeptides and proteins for gas-phase sequence analysis. In: Methods in Protein Sequence Anaylsis 1986, (ed. K.A. Walsh). Humana Press, Clifton, New Jersey. pp.213-228. |
| 23. | Simpson, R.J., Moritz, R.L., Nice, E.C. and Grego, B. (1987) A high-performance liquid chromatography procedure for recovering subnanomole amounts of protein from SDS-gel electroeluates for gas-phase sequence analysis. Eur. J. Biochem. 165:21-29. |
| 24. | Scanlon, D.B., Eefting, M.A., Lloyd, C.J., Burgess, A.W. and Simpson, R.J. (1987) Synthesis of biologically-active human transforming growth factor-( by fluorenylmethoxycarbonyl solid phase peptide chemistry. J. Chem. Soc. Chem. Commun. 25:516-518. |
| 25. | Van Damme, J., Opdenakker, G., Simpson, R.J., Rubira, M.R., Cayphas, S., Vink, A., Billiau, A. and Van Snick, J. (1987) Identification of the human 26-kD protein, interferon ß2 (IFN-B2), as a B-cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor. J. Exp. Med. 165:914-919. |
| 26. | Baldwin, G.S. Chandler, R., Seet, K.L., Weinstock, J., Grego, B., Rubira, M.R., Moritz, R.L. and Simpson, R.J. (1987) Structural studies on a 75-KDa glycoprotein isolated from porcine gastric mucosal membranes: Close homology with the 78-kDa glucose-regulated family of proteins. Protein Sequences and Data Analysis 1:7-12. |
| 27. | Simpson, R.J., Grego, B., Govindan, M.V. and Gronemeyer, H. (1987) Peptide sequencing of the chick oviduct progesterone receptor form B. Mol. Cell. Endocrinol. 52:177-184. |
| 28. | Ratajczak, T., Comber, M., Moir, R., Hahnel, R., Grego, B., Rubira, M.R. and Simpson, R.J. (1987) The amino-terminal sequence of the 85-90K nonhormone binding component of the molybdate-stabilized estradiol receptor from calf uterus. Biochem. Biophys. Res. Commun. 143:218-224. |
| 29. | Van Damme, J., Cayphas, S., Van Snick, J., Conings, R., Put, W., Lenaerts, J-P., Simpson, R.J. and Billiau, A. (1987) Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (Interleukin-6). Eur. J. Biochem. 168:543-550. |
| 30. | Simpson, R.J. and Nice, E.C. (1989) Strategies for the purification of subnanomole amounts of protein and polypeptides for microsequence analysis. In: The Use of HPLC in Receptor Purification and Characterization, (ed. A.R. Kerlavage) in series Receptor Biochemistry and Methodology (series eds. J.C. Venter and L.C. Harrison). A.R. Liss. Inc. New York, pp. 201-244. |
| 31. | Simpson, R.J. and Nice, E.C. (1987) Preparation of subnanomole amounts of protein and polypeptides for microsequencing. In: Integration and Control of Metabolic Processes: Pure and Applied Aspects, (ed. O.L. Kon). ICSU Press, New York, pp. 473-487. |
| 32. | Nice, E.C. Simpson, R.J. and Nicola, N.A. (1987) A micropreparative chromatographic strategy for the purification and sequence analysis of murine granulocyte-colony stimulating factor (mG-CSF). Chromatographia. 24:449-454. |
| 33. | Stewart, G.A., Simpson, R.J., Thomas, W.R. and Turner, K.J. (1986) The physicochemical characterization of a major protein allergen from the house dust mite, Dermatophagoides pteronyssinus. Asian Pacific J. Allergy Immunol. 4:71. |
| 34. | Simpson, R.J., Nice, E.C. and Nicola, N.A. (1987) Structural studies on the murine granulocyte colony-stimulating factor. Biol. Chem. Hoppe-Seyler. 368:1327-1331. |
| 35. | Simpson, R.J., Moritz, R.L., Lloyd, C.J., Fabri, L.J., Nice, E.C., Rubira, M.R. and Burgess, A.W. (1987) Primary structure of ovine pituitary basic fibroblast growth factor. FEBS Lett. 224:128-132. |
| 36. | Smith, D.B., Rubira, M.R., Simpson, R.J., Davern, K.M., Tiu, W.U., Board, P.G. and Mitchell, G.F (1988). Expression of an enzymatically active parasite molecule in Escherichia coli: Schistosoma japonicum glutathione S-transferase. Mol. Biochem. Parasitol. 27:249-256. |
| 37. | Burns, G.F., Lucas, C.M., Krissansen, G.W., Werkmeister, J.A., Scanlon, D.B., Simpson, R.J. and Vadas, M.A. (1988) Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to Matrix proteins by melanoma cells. J. Cell Biol. 107:1225-1230. |
| 38. | Cayphas, S., Van Damme, J., Vink, A., Simpson, R.J., Billiau, A. and Van Snick, J. (1987) Identification of an Interleukin HP1-like Plasmacytoma growth factor produced by L cells in response to viral infection. J. Immunol. 139:2965-2969. |
| 39. | Gearing, D.P., Gough, N.M., King, J.A., Hilton, D.J., Nicola, N.A., Simpson, R.J., Nice, E.C., Kelso, A. and Metcalf, D. (1987) Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J. 6:3995-4002. |
| 40. | Thomson, M., Moritz, R.L., Simpson, R.J. and Norton, R.S. (1987) Tenebrosin-A, A new cardiostimulant protein from the Australian sea anemone Actinia tenebrosa. Biochem. Int'l. 15:711-718. |
| 41. | Smith, A.I., Wallace, C.A., Moritz, R.L., Simpson, R.J., Schmauk-White, L.B., Woodcock, E.A. and Funder, J.W. (1987) Isolation, amino acid sequence and action of guinea-pig ACTH on aldosterone production by glomerulosa cells. J. Endocrinol. 115:R5-R8. |
| 42. | Chua, K.Y., Stewart, G.A., Thomas, W.R., Simpson, R.J., Dilworth, R.J., Plozza, T.M. and Turner, K.J. (1988) Sequence analysis of cDNA coding for a major house dust mite allergen, Der p1: Homology with cysteine proteases. J. Exp. Med. 167:175-182. |
| 43. | Van Snick, J., Cayphas, S., Szikora, J.P., Renauld, J-C., Van Roost, E., Boon, T. and Simpson, R.J. (1988) cDNA cloning of murine interleukin-HP1: Homology with human interleukin 6. Eur. J. Immunol. 18:193-197. |
| 44. | Thomas, W.R., Stewart, G.A., Simpson, R.J., Chua, K.Y., Plozza, T.M., Dilworth, R.J., Nisbet, A. and Turner, K.J. (1988) Cloning and expression of DNA coding for the major house dust mite allergen Der p1 in Escherichia coli. Int. Archs. Allergy Appl. Immun. 85:127-129. |
| 45. | Ramasamy, R., Simpson, R.J., Dexter, A., Keeghan, M., Reed, C., Bushell, G., Ingram, L.T., Henderson, T., Moloney, M.B., Moritz, R.L., Rubira, M.R. and Kidson, C. (1988) Isolation and partial characterisation of a 26 Kilodalton antigen from Plasmodium falciparum recognised by an inhibitory monoclonal antibody. Mol. Biochem. Parasitol. 29:125-132. |
| 46. | Simpson, R.J., Hilton, D.J., Nice., E.C., Rubira, M.R., Metcalf, D., Gearing, D.P., Gough, N.M. and Nicola, N.A. (1988) Structural characterization of a murine myeloid leukaemia inhibitory factor (LIF). Eur. J. Biochem. 175:541-547. |
| 47. | Small, D.H. and Simpson, R.J. (1988) Acetylcholinesterase undergoes autolysis to generate trypsin-like activity. Neurosci. Lett. 89:223-228. |
| 48. | Ratajczak, T., Brockway, M.J., Hahnel, R., Moritz, R.L. and Simpson, R.J. (1988) Sequence analysis of the non-steroid binding component of the calf uterine estrogen receptor. Biochem. Biophys. Res. Commun. 151:1156-1163. |
| 49. | Burgess, A.W., Lloyd, C.J., Smith, S., Stanley, E., Walker, F., Fabri, L., Simpson, R.J. and Nice, E.C. (1988) Murine epidermal growth factor: structure and function. Biochemistry. 27:4977-4985. |
| 50. | Simpson, R.J., Moritz, R.L., Rubira, M.R. and Van Snick, J. (1988) Murine hybridoma/plasmacytoma growth factor: Complete amino acid sequence and relation to human interleukin-6. Eur. J. Biochem. 176:187-197. |
| 51. | Nice, E.C. and Simpson, R.J. (1989) Micropreparative high-performance liquid chromatography of Proteins and Peptides. J. Pharmacol. Biomed. Anal. 7:1039-1053. |
| 52. | Stewart, G.A., Simpson, R.J., Moritz, R.L., Thomas, W.R. and Turner, K.J. (1988) Physico-chemical characterization of allergens Derp 1 (Dpt 12), Dpt 22 and Dpt 36 from house dust mite. In: Mite Allergy. A.L. de Weck, A. Todt (eds). The UCB Institute of Allergy, Brussels. pp. 35-38. |
| 53. | Simpson, R.J., Moritz, R.L., Begg, G.S., Rubira, M.R. and Nice, E.C. (1989) Micropreparative procedures for high sensitivity sequencing of peptides and proteins. Anal. Biochem. 177:221-236. |
| 54. | Simpson, R.J., Nice, E.C., Moritz, R.L. and Stewart, G.A. (1989) Structural studies on the allergen Der p1 from the house dust mite, Dermatophagoides pteronyssinus: Similarity with cysteine proteinases. Protein Sequence & Data Anal. 2:17-21. |
| 55. | Thomas, W.R., Chua, K.Y., Stewart, G.A., Doyle, C., Turner, K.J., Simpson, R.J. and Dilworth, R.J. (1988) Analysis and expression of cDNA coding for house dust mite allergens. DPC 1st International Symposium on Allergy and Molecular Biology, Laguna Niguel. |
| 56. | Simpson, R.J., Begg, G.S., Reid, G.E., Rubira M.R., Ward L.D., and Moritz R.L.(1989) Application of Microbore HPLC for purifying proteins and peptides for microsequence analysis in Methods in Protein Sequence Analysis, (ed. B. Wittmann-Liebold) Springer-Verlag, Berlin, pp. 256-263. |
| 57. | Begg, G.S. and Simpson, R.J. (1989) An improved injection system for on-line high sensitivity phenylthiohydantoin amino acid analysis, Methods in Protein Sequence Analysis, (ed. B. Wittmann-Liebold), Springer-Verlag, Berlin, pp. 108-111. |
| 58. | Simpson, R.J. and Moritz, R.L. (1988) Strategic approaches to protein microsequencing: Application of high sensitivity peptide mapping in "Proceedings of the Symposium on Protein Structure Function Relationship." (ed. Z.H. Zaidi), Elsevier. pp.287-297. |
| 59. | Dorow, D.S. and Simpson, R.J. (1988) Cloning and sequence analysis of a cDNA for rat epidermal growth factor. Nucl. Acids Res. 16:9338. |
| 60. | Uyttenhove, C., Simpson, R.J. and Van Snick, J. (1988) Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity. Proc. Natl. Acad. Sci. USA. 85:6934-6938. |
| 61. | Begg, G.S. and Simpson, R.J. (1989) An improved injection system for on-line liquid chromatographs : Application to high sensitivity phenylthiohydantoin amino acid analysis, in Techniques in Protein Chemistry. (ed. T.E. Hugli) Academic Press Inc. pp.79-88. |
| 62. | Simpson, R.J., Moritz, R.L., Van Roost, E. and Van Snick, J. (1988) Characterization of a recombinant murine interleukin-6: Assignment of disulphide bonds. Biochem. Biophys. Res. Commun. 157:364-372. |
| 63. | Jahnen, W., Batterham, M.P., Clarke, A.E., Moritz, R.L. and Simpson, R.J. (1989) Identification, isolation and N-terminal sequencing of style glycoproteins associated with self-incompatibility in Nicotiana alata. The Plant Cell 1:493-499. |
| 64. | Van Snick, J., Goethals, A., Renauld, J-C., Van Roost, E., Uyttenhove, C. Rubira, M.R., Moritz, R.L. and Simpson, R.J. (1989) Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40) J. Exp. Med. 169:363-368. |
| 65. | Ratajczak, T., Brockway, M.J., Hahnel, R., Moritz, R.L. and Simpson, R.J. (1988) Chemical characterization by protein sequence analysis of the bovine estrogen receptor. Biochem. Biophys. Res. Commun. 156:116-124. |
| 66. | Van Snick, J., Renauld, J-C., Simpson, R.J., Uyttenhove, C and Vink, A. (1989) Mouse IL-6: A hybridoma growth factor with multiple effects on normal B and T cells. In: Regulation of the acute phase and immune responses: Interleukin-6. Annals of the New York Academy of Sciences. 557:206-214. |
| 67. | Simpson, R.J., Moritz, R.L., Rubira, M.R., Gorman, J.J. and Van Snick, J. (1989) Complete amino acid sequence of a new murine T-cell growth factor (P40). Eur. J. Biochem. 183:715-722. |
| 68. | Simpson, R.J., and Moritz, R.L. (1989) Chromatographic fractionation of proteins at high organic solvent modifier concentrations. J. Chromatogr. 474:418-423. |
| 69. | Simpson, R.J., Ward, L.D., Reid, G.E., Batterham, M.P. and Moritz, R.L. (1989) Peptide mapping and internal sequencing of proteins electroblotted from two-dimensional gels onto polyvinylidene difluoride membranes : A chromatographic procedure for separating proteins from detergents. J. Chromatogr. 476: 345-361. |
| 70. | Thomas, W.R., Chua, K.Y., Stewart, G.A., Doyle, C.R., Turner, K.J., Simpson, R.J. and Dilworth, R.J. (1989) Analysis and expression of cDNA clones coding for house dust mite allergens. Advances in the Biosciences. 74:139-147. |
| 71. | Stewart, G.A., Thomas, W.R., Chua, K.Y., Simpson, R.J., Greene, W.K., Doyle, C. and Turner, K.J. (1989) The molecular characterization of mite allergens. Proc. Intl. Symposium on Mites and Midge Allergy. University of Tokyo, Tokyo. pp.146-169. |
| 72. | Hey, A.W., Browne, C.A., Simpson, R.J. and Thorburn, G.D. (1989) Simultaneous isolation of insulin-like growth factors I and II from adult sheep serum. Biochem. Biophys. Acta. 997:27-35. |
| 73. | Ratajczak, T., Wilkinson, S.P., Brockway, M.J., Hahnel, R., Moritz, R.L., Begg, G.S. and Simpson, R.J. (1989) The interaction site for tamoxifen aziridine with the bovine estrogen receptor. J. Biol. Chem. 264:13453-13459. |
| 74. | Simpson, R.J. and Moritz, R.L. (1991) Chromatography of proteins at high organic solvent concentrations: An inverse-gradient reversed-phase HPLC method for preparing samples for microsequence analysis. In: HPLC of Peptides and Proteins: Separation, Analysis and Conformation. R.S. Hodges and C.T. Mant (eds). CRC Press Inc., Boca Raton, USA. pp.399-408. |
| 75. | Layton, J., Nice, E.C., Dempsey, P.J., Fabri, L.J., Cui, D-f, Simpson, R.J., Morstyn, G. and Burgess, A.W. (1990) Epitope mapping of human granulocyte-macrophage colony stimulating fctor (hGM-CSF). In: Haematopoiesis, UCLA Symposium, Vol. 120. pp.11-22. |
| 76. | Norton, R.S., Bobek, G., Ivanov, J.O., Thomson, M. Fiala-Beer, E., Moritz, R.L. and Simpson, R.J. (1990) Purification and characterisation of proteins with cardiac stimulatory and haemolytic activity from the anemone Actinia tenebrosa. Toxicon. 28:29-41. |
| 77. | Ward, L.D., Reid, G.E., Moritz, R.L. and Simpson, R.J. (1990) Peptide mapping and internal sequencing of proteins from acrylamide gels. In: J.J. Villafranca (ed), Current Research in Protein Chemistry: Techniques, Structure and Function. Academic Press, Orlando, FL, USA. pp.179-190. |
| 78. | McClure, B.A., Haring, V., Ebert, P.R., Anderson, M.A., Simpson, R.J., Sakiyama, F. and Clarke, A.E. (1989) Style self-incompatibility gene products of Nicotiana alata are ribonucleases. Nature 342: 955-957. |
| 79. | Baldwin, G.S., Bacic, T., Chandler, R., Grego, R., Pederson, J., Simpson, R.J., Toh, B.H. and Weinstock, J. (1990) Isolation of transferrin from porcine gastric mucosa: Comparison with porcine serum transferrin. Comp. Biochem. Physiol. Mol. Biol. 95.:261-268. |
| 80. | Jahnen, W., Ward, L.D., Reid, G.E., Moritz, R.L. and Simpson, R.J. (1990) Internal amino acid sequencing of proteins by in situ cyanogen bromide cleavage in polyacrylamide gels. Biochem. Biophys. Res. Comm. 166:139-145. |
| 81. | Williams, N.K., Simpson, R.J., Moritz, R.L., Peide, Y., Crofts, L., Minasian, E., Leach, S.J., Wake, R.G. and Christopherson, R.I. (1990) Location of the dihydroorotase domain within trifunctional hamster dihydroorotate synthetase. Gene 94:283-288. |
| 82. | Simpson, R.J., Reid, G.E., Moritz, R.L., Morton, C. and Norton, R.S. (1990) Complete amino acid sequence of tenebrosin-C, a cardiac stimulatory and haemolytic protein from the sea anemone Actinia tenebrosa. Eur. J. Biochem. 190:319-328. |
| 83. | McNeil, H.P., Simpson, R.J., Chesterman, C.N. and Krilis, S.A. (1990) Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: ß2-glycoprotein I (apolipoprotein H). Proc. Natl. Acad. Sci. USA 87:4120-4124. |
| 84. | Nice, E., Dempsey, P., Layton, J., Morstyn, G., Cui D-F., Simpson, R.J., Fabri, L. and Burgess, A. (1990) Human granulocyte-macrophage colony-stimulating factor (hGM-CSF): Identification of a binding site for a neutralizing antibody. Growth Factors. 3:159-169. |
| 85. | Stewart, G.A., Thompson, P.J. and Simpson, R.J. (1989) Protease antigens from house dust mite. The Lancet 2:154-155. |
| 86. | Jahnen, W. and Simpson, R.J. (1990) A method for preparing proteins and peptides for microsequencing. Plant Mol. Biol. Reporter. 8:92-103. |
| 87. | Ward, L.D., Moritz, R.L., Reid, G.E. and Simpson, R.J. (1990) 2D gel electrophoresis of proteins from LIM1863 cells: identification of proteins by protein sequencing. In: Protein Engineering. (M. Ikehara, ed.), pp.295-297. Japan Scientific Societies Press, Tokyo and Springer-Verlag, Berlin. |
| 88. | Lake, F.R., Ward, L.D., Simpson, R.J., Thompson, P.J., and Stewart G.A. (1991) House dust mite-derived amylase-allergenicity and physicochemical characterisation. J. Allergy. Clin. Immunol. 87:1035-1042. |
| 89. | Giraud, A.S., Clarke, I.J, Rundle, S.E., Parker, L.M., Funder, J.W., Simpson, R.J. and Smith, A.I. (1991) Distribution, isolation and sequence analysis of the C-terminal heptapeptide of Pro-enkephalin A (YGGFMRF), from the ovine median eminence. J. Neuroendocrinology 3:215-220. |
| 90. | Toh, B-H., Gleeson, P.A., Simpson, R.J., Moritz, R.L., Callaghan, J.M., Goldkorn, I., Jones, C.M., Martinelli, T.M., Mu, F-T., Humphris, D.C., Pettitt, J.M., Mori, Y., Masuda, T., Sobieszczuk, P., Weinstock, J., Mantamadiotis, T. and Baldwin, G.S. (1990) The 60- to 90-kDa parietal cell autoantigen associated with autoimmune gastritis is a ß subunit of the gastric H+/K+-ATPase (proton pump). Proc. Natl. Acad. Sci. USA 87:6418-6422. |
| 91. | Ward, L.D. and Simpson, R.J. (1990) Tandem use of high-performance electrochromatography and inverse-gradient reversed-phase HPLC in isolating proteins for sequence analysis. J. Protein Chem. 9:283-284. |
| 92. | Ward, L.D., Reid, G.E., Moritz, R.L. and Simpson, R.J. (1990) Strategies for internal amino acid sequence analysis of proteins separated by polyacrylamide gel electrophoresis. J. Chromatogr. 519:199-216. |
| 93. | Ward, L.D., Ji, H., Whitehead, R.H. and Simpson, R.J. (1990) Development of a database of amino acid sequences for human colon carcinoma proteins separated by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 11:883-891. |
| 94. | Simpson, R.J., Moritz, R.L., Reid, G.E. and Ward, L.D. (1991) Current strategies for microscale purification of protein and peptides for sequence analysis. In: "Methods in Protein Sequence Analysis". (Jörnvall, H., Höog, J-O. and Gustavsson, A-M., Eds.), pp. 67-77, Birkhauser Verlag AG, Switzerland. |
| 95. | Inglis, A.S., Moritz, R.L., Begg, G.S., Reid, G.E., Simpson, R.J., Graffunder, H., Matschull, L. and Wittmann-Liebold, B. (1991) C-terminal sequence analysis. In: "Methods in Protein Sequence Analysis". (Jornvall, H., Hoog, J-O. and Gustavsson, A-M., Eds.), pp.23-34, Birkhauser Verlag AG, Switzerland. |
| 96. | Ward, L.D., Ji H., and Simpson, R.J. (1991) Two-dimensional electrophoresis of proteins from cultured human colonic carcinoma cells: Development of a database of amino acid sequences. In: "Techniques in Protein Chemistry: II". (Villafranca, J.J. Ed.), Academic Press. pp. 21-30. |
| 97. | Singh, M.B., Hough, T., Theerakulpisut, P., Avjioglu, A., Davies, S., Smith, P.M., Taylor, P., Simpson, R.J., Ward, L.D., McCluskey, J., Puy, R. and Knox, R.B. (1991) Isolation of cDNA encoding a newly identified major allergenic protein of rye-grass pollen: Intracellular targeting to the amyloplast. Proc. Natl. Acad. Sci. USA 88:1384-1388. |
| 98. | Chua, K.Y., Doyle, C.R. Simpson, R.J., Turner, K.J., Stewart, G.A. and Thomas, W.R. (1990) Isolation of cDNA coding for the major mite allergen Der pII by IgE plaque immunoassay. Int. Arch. Allergy Appl. Immunol. 91:118-123. |
| 99. | Sarkar, M., Hull, E., Nishikawa, Y., Simpson, R.J., Moritz, R.L., Dunn, R. and Schachter, H. (1991) Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans:UDP-N-acetylglucosamine:(-3-D-Mannoside ß-1,2-N-acetylglucosaminyltransferase I. Proc. Natl. Acad. Sci. USA 88:234-238. |
| 100. | Griffith, I.J., Smith, P.M., Pollock, J., Theerakulpisut, P., Avjioglu, A., Davies, S., Hough, T., Singh, M.B., Simpson, R.J., Ward, L.D. and Knox, R.B. (1991) Cloning and sequencing of Lol pI, the major allergenic protein of rye-grass pollen. FEBS Lett. 279:210-215. |
| 101. | Lee, E., Fernon, C., Simpson, R.J., Weir, R.C., Rice, C.M. and Dalgarno, L. (1990) Sequence of the 3' half of the Murray Valley Encephalitis Virus genome and mapping of the non-structural proteins NS1, NS3 and NS5. Virus Genes 4:3,197-213. |
| 102. | Baldwin, G.S., Seet, K.L., Callaghan, J., Toncich, G., Toh, B.H., Moritz, R.L., Rubira, M.R. and Simpson, R.J. (1991) Purification and partial amino acid sequence of human aconitase. Prot. Seq. Data Anal. 4:63-67. |
| 103. | Nice, E.C., Fabri, L., Whitehead, R.H., James, R., Simpson, R.J. and Burgess, A.W. (1991) The major colonic cell mitogen extractable from colonic mucosa is an N-terminally extended form of basic fibroblast growth factor. J. Biol. Chem. 266:14425-14430. |
| 104. | Ward, L.D. and Simpson, R.J. (1991) Micropreparative protein isolation from polyacrylamide gels following detection by high-resolution dynamic imaging: Application to microsequencing. Peptide Res. 4:187-193. |
| 105. | Klemenz, R., Frohli, E., Aoyama, A., Hoffmann, S., Simpson, R.J., Moritz, R.L. and Schafer, R. (1991) _B Crystallin accumulation is a specific response to Ha-ras and v-mos oncogene expression in mouse NIH 3T3 fibroblasts. Mol. Cell. Biol. 11:803-812. |
| 106. | Baldwin, G.S., Moritz, R.L., Rubira, M., Seet, K.L., Weinstock, J. and Simpson, R.J. (1991) Purification and partial amino acid sequence of annexin V from porcine gastric mucosal membranes. Comp. Biochem. Physiol. B - Biochem. Molec. Biol. 100:661-665. |
| 107. | Schachter, H., Hull, E., Sarkar, M., Simpson, R.J., Mortiz, R.L., Hoppener, J.W.M., and Dunn, R. (1991) Molecular-cloning of human and rabbit UDP-N-Acetylglycosamine-Alpha-3-D Mannoside-Beta-1,2-N-Acetylglucosaminyltransferase-1 Biochemical Society Transactions 19:645-648 |
| 108. | Norton, R.S., Macek, P., Reid, G. and Simpson, R.J. (1992) Relationship between the cytolysins tenebrosin-C from Actinia tenebrosa and equinatoxin II from Actinia equina. Toxicon 30:13-23. |
| 109. | Stewart, G.A., Ward, L.D., Simpson, R.J. and Thompson, P.J. (1992) The group III allergen from the house dust mite Dermatophagoides pteronyssinus is a trypsin-like enzyme. Immunology 75:29-35. |
| 110. | Boyd, A.W., Ward, L.D., Wicks, I.P., Simpson, R.J., Salvaris, E., Wilks, A., Welch, K., Loudovaris, M., Rockman, S. and Busmanis, I. (1992) Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre B cell line. J. Biol. Chem. 267:3262-3267. |
| 111. | Layton, J.E., Morstyn, G., Fabri, L.J., Reid, G.E., Burgess, A.W., Simpson, R.J. and Nice, E.C. (1991) Identification of a functional domain of human granulocyte colony-stimulating factor using neutralizing monoclonal antibodies. J. Biol. Chem. 266:23815-23823 |
| 112. | Callaghan, J.M., Toh, B-H., Simpson, R., Baldwin, G. and Gleeson, P.A. (1992) Rapid purification of the gastric H+/K+ ATPase complex by tomato-lectin affinity chromatography. Biochem. J. 283:63-68. |
| 113. | Nice, E.C., Fabri, L., Hammacher, A., Holden, J., Simpson, R.J. and Burgess, A.W. (1992) The purification of a Rap1 GTP'ase activating protein from bovine brain cytosol. J. Biol. Chem. 267:1546-1553. |
| 114. | Simpson, R.J., Moritz, R.L. and Ward, L.D. (1991) Isolation of low picomole levels of peptides and proteins for microsequence analysis: International Congress on Analytical Sciences, 7, 933-938. |
| 115. | Reid, G.E. and Simpson, R.J. (1992) Automated solid-phase peptide synthesis: Use of 2-(1H-Benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium tetrafluoroborate for coupling of tert-Butyloxycarbonyl acids. Anal. Biochem. 200:301-309. |
| 116. | Moritz, R.L., Ward, L.D. and Simpson, R.J. (1992) High-sensitivity peptide mapping utilizing reversed-phase microbore and microcolumn liquid chromatography. In: Angelletti-Hogue, R. (ed), Techniques in Protein Chemistry III, Academic Press, pp 97-106. |
| 117. | Reid, G.E. and Simpson, R.J. (1992) Use of 2-(1H-Benzotriazol-1-yl)-1,1,3,3,-tetramethyluronium tetrafluoroborate (TBTU) in rapid coupling of Boc-amino acids: Adaptation to automated solid phase-peptide synthesis. Peptides: Chemistry and Biology (Proceedings of the Twelfth American Peptide Symposium). Escom, Leiden, pp 6477-6478. |
| 118. | Simpson, R.J. (1991) Microsequence analysis of protein at low picomole levels. Today's Life Science 3(4):52-63. |
| 119. | Read, D., Shulkes, A., Fernley, R. and Simpson R. (1991) Characterization of neurotensin (6-13) from an hepatic fibrolamellar carcinoma. Peptides 12:887-892. |
| 120. | Lackmann, M., Cornish, C.J., Simpson, R.J., Moritz, R.L. and Geczy, C. (1992) Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S-100 proteins. J. Biol. Chem. 267:7499-7504. |
| 121. | Moritz, R.L., and Simpson, R.J. (1992) Application of capillary reversed-phase high-performance liquid chromatography to high-sensitivity protein sequence analysis. J. Chromatogr. 599:119-130. |
| 122. | Sarkar, M., Hull, E., Simpson, R.J., Moritz, R.L., Dunn, R. and Schachter, H. (1990) Rabbit liver UDP-N-acetylglucosamine:(-3-D-mannoside (-1,2-N-acetylglucosaminyltransferase I: characterization of a 2.5 kilobase cDNA clone. Glycoconjugate Journal 7:380. |
| 123. | Simpson, R.J. (1991) Two-dimensional acrylamide gel electrophoresis inventory of cellular protein databases. Codata Bulletin. 23:94-99. |
| 124. | Ward, L.D., Shi, P. and Simpson R.J. (1992) Binding of anti-human-Interleukin-6 monoclonal antibodies to synthetic peptides of human Interleukin-6 studied using surface plasmon resonance. Biochem. Int. 26:559-565. |
| 125. | Zhang, J., Moritz, R.L., Reid, G.E., Ward, L.D. and Simpson, R.J., (1992) Purification and characterization of a recombinant murine Interleukin-6: Isolation of N- and C- terminally truncated forms. Eur. J. Biochem. 207:903-913. |
| 126. | Liu, Z., Simpson, R.J. and Cheers, C. (1992) Recombinant IL-6 protects mice against experimental bacterial infection. Infection and Immunity 60:4402-4406. |
| 127. | Fabri, L., Nice, E.C., Ward, L.D., Maruta, H., Burgess, A.W. and Simpson, R.J. (1992) Characterization of bovine heparin-binding neurotrophic factor (HBNF): Assignment of disulfide bonds. Biochem. Int'l. 28:1-9. |
| 128. | Simpson, R.J., Tsugita, A., Celis, J.E., Garrels, J.I. and Mewes, H.W. (1992) Workshop on two-dimensional gel protein databases. Electrophoresis 13:1055-1061. |
| 129. | Hunt. J.E., Simpson, R.J. and Krilis, S.A. (1993) Identification of a region of beta-2 glycoprotein-I critical for lipid binding and anticardiolipin antibody cofactor activity. Proc. Natl. Acad. Sci. USA. 90:2141-2145. |
| 130. | Simpson, R.J., Ward, L.D. and Moritz, R.L. (1992) The use of capillary liquid chromatography and 2D-gel electrophoresis for isolating proteins for high-sensitivity protein sequence analysis. J. Prot. Chem. 11:352-353. |
| 131. | Moritz, R.L. and Simpson, R.J. (1992) Purification of proteins and peptides for sequence analysis using microcolumn liquid chromatography. J. Microcolumn Separations 4:485-489. |
| 132. | Layton, M.J., Cross, B.A., Metcalf, D., Ward, L.D., Simpson, R.J. and Nicola, N.A. (1992) A major binding protein for leukemia inhibitory factor in normal mouse serum: Identification as a soluble form of the cellular receptor. Proc. Natl. Acad. Sci. USA 89:8616-8620. |
| 133. | Suphioglu, C., Singh, M.B., Simpson, R.J., Ward, L.D. and Knox, R.B. (1993) Identification of canary grass (Phalaris aquatica) pollen allergens by immunoblotting: IgE and IgG antibody-binding studies. Allergy 48: 273-281. |
| 134. | Atkinson, A.H., Heath, R.L., Simpson, R.J., Clarke, A.E. and Anderson, M.A. (1993) Proteinase inhibitors in Nicotiana alata stigmas are derived from a precursor protein which is processed into five homologous inhibitors. Plant Cell 5:203-213. |
| 135. | Nicola, N.A., Cross, B. and Simpson, R.J. (1993) The disulfide bond arrangement of leukemia inhibitory factor: homology to oncostatin M and structural implications. Biochem. Biophys. Res. Commun. 190: 20-26. |
| 136. | Lackamann, M., Rajusekariah, P., Iismaa, S.E., Jones, G., Cornish, C.J., Hu, S., Simpson, R.J., Moritz, R.L. and Geczy, C.L. (1993) Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10. J. Immunol. 150: 2981-2991. |
| 137. | Lake, F.R., Ward, L.D., Simpson, R.J., Thompson, P.J., and Stewart, G.A. (1991) Allergenicity and physicochemical characterization of house dust mice derived amylase. Int. Arch. Allergy Appl. Immunol. 94:357-358. |
| 138. | Leedman, P.J., Faulkner-Jones, B., Cram, D.S., Harrison, P.J., West, J., O'Brien, E., Simpson, R., Coppel, R.L. and Harrison, L.C. (1993) Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulins. Proc. Natl. Acad. Sci. USA 90:5594-5598. |
| 139. | Ji, H., Baldwin, G.S., Burgess, A.W., Moritz, R.L., Ward, L.D. and Simpson, R.J. (1993) Epidermal growth factor induces serine phosphorylation of stathmin in a human colon carcinoma cell line (LIM 1215). J. Biol. Chem. 268:13396-13405. |
| 140. | Fabri, L., Maruta, H., Muramatsu, H., Muramatsu, T., Simpson, R.J., Burgess, A.W. and Nice, E.C. (1992) Structural characterization of native and recombinant forms of the neurotrophic cytokine MK. J. Chromatogr. 28:1-9. |
| 141. | Lackmann, M., Cornish, C.J., Simpson, R.J., Moritz, R.L., Reid, G.E. and Geczy, C.L. Isolation and structural analysis of a murine chemotactic protein CP-10. In: Progress in Biomedical Research, Vol 2, Pathophysiology and pharmacology of cytokines, (Eds, Ghezzi & Montovani), 1992, pp.273-280, Biomedical Press. |
| 142. | Ratajezak, T., Carrello, A., Mark, P.J., Warner, B.J., Simpson, R.J., Moritz, R.L. and House, A.K. (1993) The cyclophilin component of the unactivated estrogen receptor contains a tetratricopeptide repeat domain and shares identity with p59 (FKB959). J. Biol. Chem. 268:13187-13192. |
| 143. | Ward, L.D., Hammacher, A., Zhang, J-G., Weinstock, J., Yasukawa, K., Morton, C.J., Norton, R.S. and Simpson, R.J. (1993) Role of the C-terminus in the activity, conformation and stability of interleukin-6. Protein Science 2:1478-1481. |
| 144. | Ward, L.D., Zhang, J-G., Checkley, G., Preston, B. and Simpson, R.J. (1993) Effect of pH and denaturants on the folding and stability of murine interleukin-6. Protein Science 2:1291-1300. |
| 145. | Ward, L.D., Hammacher, A., Zhang, J.G., Discolo, J., Tu, G.F., Moritz, R.L., Morton, C.J., Norton, R.S., and Simpson, R.J. Role of C-Terminal region of murine interleukin-6 in biological-activity and structural conformation (1993) Journal of Cellular Biochemistry. 17B: 120-120 |
| 146. | McKinstry, W.J., Welch, K.L., Martin, M., Moritz, R.L., Ward, L.D., Simpson, R.J., Boyd, A.W., and Nicola, N.A. (1993) Purification of a fragment of human-complement factor BB having self-renewal activity on a murine hematopoietic progenitor-cell line. Experimental Hematology. 21:1148-1148 |
| 147. | Morton, C.J., Simpson, R.J. and Norton, R.S. (1994) Solution structure of synthetic peptides corresponding to the C-terminal helix of interleukin-6. Eur. J. Biochem. 219:97-107. |
| 148. | Abo, S., Bernard, C.C.A., Webb, M., Johns, T.G., Alafacic, A., Ward, L.D., Simpson, R.J. and Kerlero de Rosbo, N. (1993) Preparation of highly purified human myelin oligodendrocyte glycoprotein in quantities sufficient for encephalitogenicity and immunogenicity studies. Biochem. Mol. Biol. Int. 30:945-958. |
| 149. | Simpson, R.J. (1994) 2D-gel cellular protein databases: Towards integrating protein and DNA sequence and chromosomal mapping information. In Proceeding of the 13th International CODATA Conference, Beijing, 1992 (Gleaser, P. Ed.). |
| 150. | Stewart, G.A., Bird, C.H., Thompson, P.J., Ward, L.D. and Simpson, R.J. (1993) Similarity between a Lysozyme-like Enzyme from the Dust Mite and the Group-II allergens. J. Allergy Clin. Immunol. 91:356-356 |
| 151. | Moritz, R.L. and Simpson, R.J. (1993) Capillary liquid chromatography: A tool for protein structural analysis. In Methods in Protein Sequence Analysis (K. Imahori and F. Sakiyama, Eds), pp.3-10, Plenum Press, New York. |
| 152. | Moritz, R.L. and Simpson, R.J. (1993) Capillary reversed-phase liquid chromatography: Application to high sensitivity protein sequence analysis. In Biomedical Products, pp. 48-50. |
| 153. | Bendiak, B., Ward, L.D. and Simpson, R.J. (1993) Proteins of the Golgi apparatus. Purification to homogeneity, N-terminal sequence, and unusually large Stokes radius of the membrane-bound form of UDP-galactose:N-acetylglucosamine (1-4galactosyltransferase from rat liver. Eur. J. Biochem. 264:405-417. |
| 154. | Zhang, J-G., Reid, G.E., Moritz, R.L., Ward, L.D. and Simpson, R.J. (1993) Specific covalent modification of the tryptophan residues in murine interleukin-6. Eur. J. Biochem. 217:53-59. |
| 155. | Stapleton, A.M.F., Simpson, R.J. and Ryall, R.L. (1993) Crystal matrix protein is related to human prothrombin. Biochem. Biophys. Res. Commun. 195:1199-1203. |
| 156. | Simpson, R.J. and Renauld, J-C. (1994) Interleukin-9, in "Guidebook to Cytokines and Their Receptors", (N.A. Nicola, Ed) at Oxford University Press, Sambrook and Tooze Publications, pp 79-81. |
| 157. | Ward, L.D., Hammacher, A., Chang, J., Zhang, J-G., Discolo, G., Moritz, R.L., Yasukawa, K. and Simpson, R.J. (1994) Reconstitution in vitro of the interleukin-6/interleukin-6 receptor interaction: Direct monitoring using a biosensor employing surface plasmon resonance detection, in "Techniques in Protein Chemistry V" (J.W. Crabb, Ed.), Academic Press, Orlando, FL. pp. 331-338. |
| 158. | Hong Ji, Whitehead, R.H., Reid, G.E., Moritz, R.L., Ward, L.D. and Simpson, R.J. (1994) Two-dimensional electrophoretic analysis of proteins expressed by normal and cancerous human crypts: Application of mass spectrometry to peptide-mass fingerprinting. Electrophoresis 15: 391-405. |
| 159. | Ward, L.D., Howlett, G.J., Hammacher, A., Weinstock, J., Yasukawa, K., Simpson, R.J. and Winzor, D.J. (1995) Use of a biosensor with surface plasmon resonance detection for the determination of binding constants: Measurement of interleukin-6 binding to the soluble interleukin-6 receptor. Biochemistry 34:2901-2907. |
| 160. | Ward, L.D., Howlett, G.J., Discolo, G., Yasukawa, K., Hammacher, A., Moritz, R.L. and Simpson, R.J. (1994) High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130. J. Biol. Chem. 269:23286-23289. |
| 161. | Symons, F.M., Murray, P.J., Hong Ji, Simpson, R.J., Osborn, A.H., Cappai, R. and Handman, E. (1994) Characterization of a polymorphic family of integral membrane proteins in promastigotes of different Leishmania species. Mol. Biochem. Parisitol. 67: 103-113. |
| 162. | Tang, Y-h., Cui, D-f., Zhang, Y-s. and Simpson, R.J. (1993) Synthesis of B22 Asp human insulin and its biological activity. In "Peptides: Biology and Chemistry: Proceedings of the 1992 Chinese Peptide Symposium ". (Du, Y-c., Tam, P., and Zhang T-s, Eds.), ESCOM Science Publishers B.V., pp. 23-25. |
| 163. | Moritz, R.L., Eddes, J., Ji, H., Reid, G.E. and Simpson, R.J. (1995) Rapid Separation of Proteins and Peptides using Conventional Silica-Based Supports: Identification of 2-D Gel Proteins Following In-Gel Proteolysis. In "Techniques in Protein Chemistry VI". (J.W. Crabb, Ed.), Academic Press, Orlando, FL, pp.311-319. |
| 164. | Ward, L.D., Howlett, G.J., Moritz, R.L., Hammacher, A., Yasukawa, K. and Simpson, R.J. (1995) Studies of Cytokine - Cytokine Receptor Interactions: Influence of Ligand Dimerization. In "Techniques in Protein Chemistry VI". (J.W. Crabb, Ed.), Academic Press, Orlando, FL. pp.417-425. |
| 165. | Hammacher, A., Ward, L.D., Weinstock, J., Treutlein, H., Yasukawa, K. and Simpson, R.J. (1994) Structure - Function analysis of human interleukin-6: Identification of two distinct receptor binding regions. Protein Science. 3:2280-2293. |
| 166. | Liu, Zhanqi, Simpson, R.J. and Cheers, C. (1994) Resistance to Listeria Monocytogenes. Journal of Immunology 152: 5375-5380. |
| 167. | Inglis, A.S, Reid, G.E. and Simpson, R.J. (1995). Chemical Techniques Employed for the Primary Structure Analysis of Protein and Peptides. In: "Interface between Chemistry and Biochemistry" (Jollés, P. and Jörnvall, H., Eds.), Birkhäuser Verlag A.G., Basel. pp. 141-171. |
| 168. | Hammacher A., Ward L.D., Weinstock, J. and Simpson, R.J. (1995). Structural and Biological Characterization of Murine-Human Interleukin-6 (IL-6) Chimaeras. Interleukin-6 Type Cytokines. Annals of the New York Academy of Sciences 762: 422-423. |
| 169. | Du. H., Simpson, R.J., Moritz, R.L., Bacic, A. and Clarke, A.E. (1994) Isolation and Cloning of a cDNA Encoding an Arabinogalactan-Protein (AGP) from the Styles of Nicotiana alata. Plant Cell 6: 1643-1653. |
| 170. | Chen, C-g., Pu, Z-y., Moritz, R.L., Simpson, R.J., Bacic, A., Clarke, A.E. and Mau, S-l. (1994) Molecular cloning of a gene encoding an arabinogalactan-protein from pear (Pyrus communis) cell suspension culture. Proc. Natl. Acad. Sci. USA 91: 10305-10309. |
| 171. | Moritz, R.L., Eddes, J., Ji, H., Reid, G.E. and Simpson, R.J. (1994). High-speed chromatographic separation of proteins and peptides: Application to rapid peptide mapping of in-gel digested proteins. J. Prot. Chem. 13:486-487. |
| 172. | Ward L.D., Howlett G.J., Hammacher, A., Moritz, R.L. and Simpson, R.J. (1995). Stoichiometry of the Interleukin-6 High Affinity Receptor Complex. Interleukin-6 Type Cytokines. Annals of the New York Acad. Sci. 762:471-473. |
| 173. | Moritz, R.L., Eddes, J. and Simpson, R.J. (1995). High-speed Chromatographic Separation of Proteins and Peptides for High Sensitivity Microsequence Analysis. In: "Methods in Protein Structural Analysis" (Atassi, M.Z and Appella E., Eds.). Plenum Press, New York. pp. 27-38. |
| 174. | Mulhern, T.D., Howlett, G.J., Reid, G.E., Simpson, R.J., McColl, D.J., Anders, R.F. and Norton, R.S. (1995) Solution structure of a polypeptide containing four heptad repeat units from a metozoite surface antigen of Plasmodium falciparum. Biochemistry 34:3479-3491. |
| 175. | Ward, L.D. and Simpson, R.J. Proteins and Peptides, Isolation for sequence analysis of. (1995) In: "Molecular Biology and Biotechnology, A Comprehensive Desk Reference", (R.A. Meyers, Ed.) VCH, New York, pp. 767-771. |
| 176. | Tu, G-F., Reid, G.E., Zhang, J-G., Moritz, R.L. and Simpson, R.J. (1995) C-terminal extension of truncated recombinant proteins in E.coli with a 10Sa RNA decapeptide. J. Biol. Chem. 270:9322-9326. |
| 177. | Moritz, R.L., Reid, G.E., Ward, L.D. and Simpson, R.J. (1994) Capillary HPLC: A method for protein isolation and peptide mapping. Methods: A Companion to Methods in Enzymology 6:213-226. |
| 178. | Smith, P.M., Avjioglu, A., Ward, L.D., Simpson, R.J., Knox, R.B. and Singh, M.B. (1994) Isolation and characterization of group-1 isoallergens from Bermuda grass pollen. Int. Arch. Allergy Immunol. 104:57-64. |
| 179. | Heath, R.L., Barton, P.A., Simpson, R.J., Reid, G.E., Lim, G., and Anderson, M.A. (1995) Characterization of the protease processing sites in a multidomain proteinase inhibitor precursor from Nicotiana Alata. Eur. J. Biochem. 230:250-257. |
| 180. | Morton, C.J., Bai, H., Zhang, J.-G., Hammacher, A., Norton, R.S., Simpson, R.J., and Mabbutt, B.C. (1995) NMR Studies of the solution properties of recombinant murine interleukin-6. Biochem. Biophys. Acta. 1249:189-203. |
| 181. | Reid, G.E., Ji, H., Eddes, J.S., Moritz, R.L and Simpson, R.J. (1995) Non-reducing two-dimensional polyacrylamide gel electrophoretic analysis of human colonic proteins. Electrophoresis 16:1120-1130. |
| 182. | Dorow, D.S., Devereux, L., and Simpson, R.J. (1995) Mixed lineage kinases - A new family of protein kinases containing a double leucine zipper domain, a basic motif and a SH3 domain. In: "Methods in Protein Structural Analysis" (Atassi, M.Z., and Appella, E., Eds.) Plenum Press, New York, pp 369-380. |
| 183. | Liu, Z., Simpson, R.J., and Cheers, C. (1995) Role of IL-6 in T-Cell activation during primary and secondary infection with Listeria monocytogenes. Infection and Immunity 63(7): 2790-2792. |
| 184. | Liu, Z., Simpson, R.J., and Cheers, C. (1995) Interaction of interleukin-6, tumour necrosis factor and interleukin-1 during Listeria Infection. Immunology 85: 562-567. |
| 185. | Tang, Y., Grover, P.K., Moritz, R.L., Simpson, R.J., and Ryall, R.L. (1995) Is nephrocalcin related to the urinary derivative (bikunin) of inter-(-trypsin inhibitor. Br. J. Urol. 76: 425-430. |
| 186. | Mau, S-L., Chen, C-G., Simpson, R.J., Pu, Z-Y., Bacic, A., and Clarke, A.E. (1995) Molecular cloning of cDNA's encoding the protein backbones of arabinogalactan-proteins from the filtrate of suspension cultured cells of Pyrus communis and Nicotiana alata. Plant J. 8:269-281. |
| 187. | Ward, L.D., Matthews, J.M., Zhang, J.-G., and Simpson, R.J. (1995) Equilibrium Denaturation of Recombinant Murine Interleukin-6: Effect of pH, Denaturants, and Salt on Formation of Folding Intermediates. Biochemistry 34:11652-11659. |
| 188. | Ryall, R.L., Grover, P.K., Stapleton, A.M.F., Barrell, D.K., Tang, Y., Moritz, R.L., and Simpson, R.J. (1995) The urinary Urinary F1 Activation Peptide of Human Prothrombin is a potent inhibitor of calcium-oxalate crystallization in undiluted human urine in vitro. Clin. Sci. 89:533-541. |
| 189. | Simpson, R.J., and Moritz, R.L. (1995). Purification of Small Peptides from Biological Sources. In: "Proteins LABFAX" (Price, N., Ed.), BIOS Scientific Publishers, Oxford. pp. 71-77. |
| 190. | D'Agostaro G.A.F., Zingoni, A., Moritz, R.L., Simpson, R.J., Schachter, H., and Bendiak, B. (1995) Molecular cloning and expression of cDNA encoding the rat UDP-N-Acety-lglucosamine: (-6-D-Mannoside (-1,2-N-Acetyl-glucosaminyl-transferase II. J. Biol. Chem. 270:15211-15221. |
| 191. | Dorow, D.S., Devereux, L., Tu, G.F., Price, G., Nicholl, J.K., Sutherland, G.R., and Simpson, R.J. (1995) Complete-nucleotide sequence, expression and chromosomal localisation of human mixed-lineage kinase 2. Eur. J. Biochem. 234:492-500. |
| 192. | Ryall, R.L., Grover, P.K., Stapleton, A.M.F., Tang, Y., Moritz, R.., and Simpson, R.J. (1995) Effect of urinary prothrombin fragment-1 on calcium-oxlate crystallization in undiluted human urine. Kidney International 48: 910-910 |
| 193. | Norton, R.S., Mulhern, T.D., Reid, G.E., Simpson, R.J., Howlett, G.J., and Anders, R.F. (1995) Solution structure of a polypeptide containing 4 heptad repeat units from a merozoite surface antigen of Plasmodium-falciparum. Biochemistry 34:3479-3491 |
| 194. | Dell'Angelica, E.C., Schleicher, C.H., Simpson, R.J., and Santome, J.A. (1996) Complex assembly of calgranulins A and B, two S100-like calcium-binding proteins from pig granulocytes. Int. J. Biochem. Cell Biol. 28:53-62. |
| 195. | Simpson, R.J., Zhang, J-G., Dorow, D.S., Reid, G.E., Moritz, R.L., and Tu, G-F. (1996) Identification of Truncated E. coli-expressed proteins with a novel C-terminal 10Sa RNA Decapeptide Extension. In: "Techniques in Protein Chemistry VII" (Marshak, D.R., Ed.), Academic Press, San Diego, pp. 481-492. |
| 196. | Matthews, J.M., Ward, L.D., Zhang, J-G., and Simpson, R.J. (1996) The association of unfolding intermediates during the equilibrium unfolding of recombinant murine interleukin-6. In: "Techniques in Protein Chemistry VII" (Marshak, D.R., Ed.), Academic Press, San Diego, pp. 449-458. |
| 197. | Lackmann, M., Bucci, T., Mann, R.J., Kravets, L.A., Viney, E., Smith, F., Moritz, R.L., Carter, W., Simpson, R.J., Nicola, N.A., Mackwell, K., Nice, E.C., Wilks, A.F., and Boyd, A.W. (1996) Purification of a ligand for the Eph-like receptor HEK using a novel biosensor-based affinity detection approach. Proc. Natl. Acad. Sci. USA 93: 2523-2527. |
| 198. | Hammacher, A., Simpson, R.J., and Nice, E.C. (1996) The interleukin-6 (IL-6) partial antagonist (Q159E, T162P) IL-6 interacts with the IL-6 receptor and gp130, but fails to induce a stable hexameric receptor-complex. J. Biol. Chem. 271: 5464-5473. |
| 199. | Hammacher, A., Nice, E.C., Simpson, R.J. (1995) Kinetic analysis of the interaction of an interleukin-6 (IL-6) antagonist with the IL-6 receptor and gp130. In: "Proceedings of the 5th European BIA Symposium. pp. 66-69. |
| 200. | Du, H., Simpson, R.J., Clarke, A.E., and Bacic, A. (1996). Molecular Characterization of a Stigma-Specific Gene Encoding an Arabinogalactan-protein (AGP) from Nicotiana alata. Plant Journal. 9:313-323. |
| 201. | Gonda, T.J., Favier, D., Ferrao, P., MacMillan, E.M., Simpson, R.J., and Tavner, F. (1996). The c-Myb negative regulatory domain. In: "Molecular aspects of myeloid stem cell development" (Wolff, L., Perkins, A.S., Eds.), Springer-Verlag, Berlin. pp. 99-112. |
| 202. | King, C., Simpson, R.J., Moritz, R.L., Reid, G., Thompson, P.J., and Stewart, G.A. (1996) The isolation and characterisation of a novel collagenolytic serine protease allergen (Der p9) from the dust mite Dermatophagoides pteronyssinus. J. Allergy Clin. Immunol. 98: 739-747. |
| 203. | Ward, L.D., Hammacher, A., Howlett, G.J., Matthews, J.M.., Fabri, L., Moritz, R.L., Nice, E.C., Weinstock, J., and Simpson, R.J. (1996). Influence of Interleukin-6 (IL-6) dimerization on formation of the high-affinity hexameric IL-6 receptor complex. J. Biol. Chem. 271: 20138-20144. |
| 204. | Moritz, R.L., Eddes, J.S., Reid, G.E., and Simpson, R.J. (1996) S-pyridylethylation of intact polyacrylamide gels and in situ digestion of electrophoretically-separated proteins: A rapid mass spectrometric method for identifying cysteine-containing peptides. Electrophoresis. 17: 907-917 |
| 205. | Ilg, T., Stierhof, Y-D., Craik, D., Simpson, R.J., Handman, E., Bacic, A. (1996). Purification and structural characterization of a filamentous, mucin-like proteophosphoglycan secreted by Leishmania parasites. J. Biol. Chem. 271: 21583-21596.. |
| 206. | Hodder, A.N., Crewther, P.E., Matthew, M.L.S.M., Reid, G.E., Moritz, R.L., Simpson, R.J., Anders, R.S. (1996) The disulfide bond structure of Plasmodium apical antigen-1. J. Biol. Chem. 271: 29466-29452. |
| 207. | Simpson, R.J., Reid, G.E., Moritz, R.L., Ward, L.D., (1996) Protein and Peptides, Isolation for Sequence of. In Encyclopedia of Molecular Biology and Molecular Medicine. (Blackwell Scientific Publications). pp. 173-185 |
| 208. | Egerton, M., Moritz, R.L., Druker, B., and Simpson, R.J. (1996) Identification of the 70KD heat shock cognate protein (Hsc70) and (-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. Biochem. Biophys. Res. Commun. 224: 666-674. |
| 209. | Catimel, B., Ritter, G., Old, L.J., Cohen, L., Nerrie, M., White, S., Heath, J., Demediuk, B., Domagala, T., Flegg, R., Lee, F.T., Scott, A.M., Hong, J., Mortiz, R., Simpson, R.J., Burgess, A.W., and Nice E.C. (1996) Purification and characterisation of a novel differentiation marker for normal and transformed colonic epithelium. J. Biol. Chem. 271: 25664-25670. |
| 210. | Simpson, R.J., Hammacher, A., Smith, D.K., Matthews, J.M., and Ward, L.D. (1997) Interleukin-6: Structure-function relationships. Protein Science. 6: 929-955. |
| 211. | Rasmussen R.K., Ji H., Eddes, J.S., Moritz, R.L., Reid, G.E., Simpson, R.J. (1997) Two-dimensional electrophoretic analysis of human breast carcinoma proteins: Mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2. Electrophoresis. 18: 588-598. |
| 212. | Ji H., Reid, G.E., Moritz, R.L., Eddes, J.S., Burgess, A.W., Simpson, R.J. (1997) A two-dimensional gel database of human colon carcinoma proteins. Electrophoresis 18: 605-613. |
| 213. | Zhang, J-G., Hilton, D.J., Willson, T.A., McFarlane, C., Roberts, B.A., Moritz, R.L., Simpson, R.J., Alexander, W.A., Metcalf, D., Nicola, N.A. (1997) Identification, purification and characterization of a soluble IL-13-binding protein: Evidence that it is distinct from the cloned IL-13 receptor and Il-4 receptor (-chains. J. Biol. Chem. 272:9474-9480. |
| 214. | Tong, D., Moritz, R.L., Eddes, J.S., Reid, G.E., Rasmussen, R.K., Dorow, D.S., Simpson, R.J. (1997) Fabrication of stable packed capillary reversed-phase columns for protein structural analysis. J. Prot. Chem. 16:425-431. |
| 215. | Heath, J.K., White, S.J., Johnstone, C.N., Catimel, B., Simpson, R.J., Moritz, R.L., Tu, G-F., Ji, H., Whitehead, R.H., Groenen, L.C., Scott, A.M., Ritter, G., Cohen, L., Welt, S., Old, L.J., Nice, E.C., Burgess, A.W. (1997) The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily. Proc. Natl. Acad. Sci. U.S.A. 94: 469-474. |
| 216. | Ji, H., Moritz, R.L., Reid, G.E., Ritter, G., Catimel, B., Nice, E.C., Heath, J.K., White, S.J., Welt, S., Old, L.J., Burgess, A.W., Simpson, R.J. (1997) Electrophoretic analysis of the novel antigen for the gastrointestinal-specific monoclonal antibody, A33. Electrophoresis 18: 614-621. |
| 217. | Zhang, J-G., Matthews, J.M., Ward, L.D., Simpson, R.J. (1997) Disruption of the disulfide bonds of recombinant murine interleukin-6 induces formation of a partially unfolded state. Biochemistry 36: 2380-2389. |
| 218. | Matthews, J.M., Ward, L.D., Hammacher, A., Norton, R.S., Simpson, R.J. (1997) Interaction of Histidine 31 and Tryptophan 34 in the structure, self-association, and folding of murine interleukin-6: Biochemistry 36:6187-6196. |
| 219. | Hammacher A., Reid, G.E., Moritz, R.L., Simpson, R.J. (1997) Identification and characterisation of recombinant murine interleukin-6 with a C-terminal pentapeptide extension using capillary reversed phase HPLC-MS and Edman degradation. Biomed. Chrom. 11: 337-342. |
| 220. | Holmes, M.L., Scopes, R.K., Moritz, R.L., Simpson, R.J., Englert, C., Pfeifer, F., Dyall-Smith, M.L. (1997) Purification and analysis of an extremely halophilic (-galactosidase from Haloferax alicantei. Biochimica et Biopysica Acta 1337: 276-286. |
| 221. | Ji, H. and Simpson, R.J. (1999) Non-reducing 2-D Polyacrylamide Gel Electrophoresis. In: Methods in Molecular Biology, Vol. 112: 2-D Proteome Analysis Protocols, Link, A.J. (ed.), Humana Press Inc., Totawa, NJ, USA. pp. 255-263. |
| 222. | Simpson, R.J. and Reid, G.E. (1998) Sequence analysis of gel-resolved proteins. In Gel Electrophoresis of proteins - A practical approach (3rd edition), Hames, B.D. (ed.), IRL Press at Oxford University Press. pp. 237-267. |
| 223. | Ritter, G., Moritz, R.L., Ji, H., Cohen, L.C., Nice, E.C., Catimel, B., Heath, J.K., White, S.J., Welt, S., Burgess, A.W., Old, L.J., and Simpson, R.J. (1997) Characterization of post-translational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium. Biochem. Biophys. Res. Commun. 236:682-686. |
| 224. | Menting, J.G.T., Tilley L., Deady, L.W., Ng, K., Simpson, R.J., Cowman, A.F., and Foley, M. (1997) The antimalarial drug, chloroquine, interacts with lactate dehydrogenase from Plasmodium falciparum. Molec. Biochem. Parasitology 88:215-224. |
| 225. | Moritz, R.L., Ritter, G., Catimel, B., Cohen, L.S., Welt, S., Old, L.J., Burgess, A.W., Nice, E.C. and Simpson, R.J. (1998) Microsequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium. J. Chromatogr. 798:91-101. |
| 226. | Chen, Y.C., Reid, G.E., Simpson, R.J. and Truscott, R.J.W. (1998) Molecular evidence for the involvement of alpha crystallin in the colouration/crosslinking of crystallins in age-related nuclear cataract. Exp. Eye Res. 65:835-840. |
| 227. | Tavner, F.J., Simpson, R.J., Tashiro, S., Favier, D., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., Keough, R.A., Ishii, S., and Gonda, T.J. (1998) Molecular Cloning reveals that the p160 myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb. Mol. Cell Biol. 18:989-1002. |
| 228. | Reid, G.E., Rasmussen, R.K., Dorow, D.S. and Simpson, R.J. (1998) Capillary column chromatography improves sample preparation for mass spectrometric analysis: Complete characterization of human (-enolase from two-dimensional gels following in-situ proteolytic digestion. Electrophoresis 19:946-955. |
| 229. | Rasmussen, R.K., Ji, H., Eddes, J.S., Zugaro, L.M., Reid, G.E., Simpson, R.J., and Dorow, D.S. (1998) Two-dimensional gel database of human breast carcinoma cell expressed proteins: an update. Electrophoresis 19: 818-825. |
| 230. | Rasmussen, R. K., Ji, H., Eddes, J.S., Moritz, R.L., Reid, G.E., Simpson, R.J., and Dorow, D.S. (1998) Two-dimensional electrophoretic analysis of mixed lineage kinase 2 N-terminal domain binding proteins. Electrophoresis 19: 809-817. |
| 231. | Zugaro, L.M., Reid, G.E., Ji, H., Eddes, J.S., Murphy, A.C., Burgerss, A.W., and Simpson, R.J. (1998) Characterization of rat brain isoforms by two-dimensional gel electrophoresis, matrix-assisted laser-desorption and electrospray ionization -ion trap mass spectrometry. Electrophoresis 19: 867-876. |
| 232. | Chataway, T.K., Whittle, A.M., Lewis, M.D., Bindloss, C.A., Moritz, Simpson, R.J., R.L., Hopwood, J.J., and Meikle, P.J. (1998) Development of a two-dimensional gel electrophoresis database of human lysosomal proteins. Electrophoresis 19:834-836. |
| 233. | Matthews, J.M., Hammacher, A., Howlett, G.J., and Simpson, R.J. (1998) Physicochemical characterization of an antagonistic human interleukin-6 dimer. Biochemistry 37:10671-10680. |
| 234. | Hammacher, A., Richardson, R.T., Layton, J.E., Smith, D.K., Angus, L.J.L., Hilton, D.J., Nicola, N. A., Wijdenes, J., and Simpson, R.J. (1998) The immunoglobulin-like module of gp130 is required for signaling interleukin-6, but not by leukemia inhibitory factor. J. Biol. Chem. 273:22701-22707. |
| 235. | Reid, G.E., Simpson, R.J., and O'Hair, R.A.J. (1998) Mass spectrometric and ab initio study of the pathways for dehydration of simple glycine and cysteine-containing peptide [M+H]+ ions. J. Am. Soc. Mass Spectrom. 9:945-956. |
| 236. | Ford, C.M., Paltridge, N.G., Rathjen, J. P., Moritz, R.L., Simpson, R.J. and Symons, R.H. (1998) Rapid and informative assays for Yd2, the barley yellow dwarf virus resistance gene, based on the nucleotide sequence of a closely linked gene. Molec. Breeding 4:23-31. |
| 237. | He, H., Watanabe, T., Zhan, X., Huang, C., Schuuring, E., Fukami, K., Takenawa, T., Kumar, C.C., Simpson, R.J., and Maruta, H. (1998) Role of phoshatidylinositol 4,5-biphosphate in Ras/Rac-induced disruption of the cortactin-actomysin II complex and malignant transformation. Mol. Cell Biol. 18:3829-3837. |
| 238. | Grover, P.K., Moritz, R.L., Simpson, R.J. and Ryall, R.L. (1998) Inhibition of growth and aggregation of calcium oxalate crystals in vitro. A comparison of four human proteins. Eur. J. Biochem. 253:637-644. |
| 239. | Rasmussen, R.K., Rusak, J., Price, G., Robinson, P.J., Simpson, R.J., and Dorow, D.S. (1998) Mixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances GTPase activation by phospholipid. Biochem. J. 335:119-124. |
| 240. | Novak, U., Ji, H., Kanagasundaram, V., Simpson, R.J., and Paradiso, L. (1998) STAT3 forms stable homodimers in the presence of divalent cations prior to activation. Biochem. Biophys. Res. Commun. 247:558-563. |
| 241. | Chataway, T.K., Whittle, A. M., Lewis, M.D., Bindloss, C.A., Davey, R.C.A., Moritz, R.L., Simpson, R.J., Hopwood, J.J., and Meikle, P.J. (1998) Two-dimensional mapping and microsequencing of lysosomal proteins from human placenta. Placenta 19:643-654. |
| 242. | Moritz, R. L. and Simpson, R. J. (1999) Interleukins. In: The Encyclopedia of Molecular Biology (Creighton, TE ed.), John Wiley and Sons, New York, pp. 1293-1296. |
| 243. | Reid, G. E., O'Hair, R. A. J., Styles, M. L., McFadyen, W. D. and Simpson, R. J. (1998) Gas Phase Ion-molecule Reactions in a Modified Ion Trap: H/D Exchange of Non-covalent Complexes and Coordinatively Unsaturated Platinum Complexes. Rapid Commun. Mass Spectrom. 12:1701-1708. |
| 244. | Zhang, J-G., Zhang, Y., Owczarek, M., Ward, L.D., Moritz, R.L., Simpson, R.J., Yasukawa, K., and Nicola, N.A. (1998) Identification and characterization of two distinct truncated forms of gp130 and a soluble form of leukemia inhibitory factor receptor (-chain in normal human urine and plasma. J. Biol. Chem. 273:10798-10805. |
| 245. | Cole, A. R., Hall, N. E., Treutlein, H., Eddes, J. S., Reid, G. E., Moritz, R. L.,. and Simpson, R. J. (1999) Disulfide Bond Structure and N-Glycosylation Sites of the Extracellular Domain of the Human Interleukin-6 Receptor. J. Biol. Chem. 274:7207-7215. |
| 246. | Moritz, R. L., Ward, L. D., Tu, G-F, Fabri, L. J., Ji, H. Yasukawa, K. and Simpson, R. S. (1999) The N-terminus of gp130 is critical for the formation of the high affinity interleukin-6 receptor. Growth Factors 16:265-278. |
| 247. | Zhang, J-G., Farley, A., Nicholson, S. E., Willson, T. A., Zugaro, L. M., Simpson, R. J., Moritz, R. J., Carey, D., Richardson, R., Hausmann, G., Kile, B., Kent, S. B. H., Alexander, W. S., Hilton, D. J., Nicola, N. A., and Baca, M. (1999) The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple proteins to proteosomal degradation. Proc. Natl. Acad. Sci. USA 96:2071-2076. |
| 248. | Castellanos-Serra, L., Proenza, W., Huerta, V., Moritz, R.L., and Simpson, R.J. (1999) Proteome analysis of polyacrylamide gel separated proteins visualized by reversible negative staining using imidazole-zinc salts. Electrophoresis 20:732-737. |
| 249. | Torres, A.M., Wang, X., Fletcher, J. I., Alewood, D., Alewood, P. F., Smith, R., Simpson, R. J., Nicholson, G. M., Sutherland, S. K., Gallagher, C. H., King, G. F., and Kuchel, P. W. (1999) Solution structure of a defensin-like peptide from platypus venom. Biochem. J. 341:785-794. |
| 250. | Matthews, JM., Norton, RS., Hammacher, A., and Simpson, RJ (2000) The single mutation Phe173>Ala induces a molten globule-like state in murine interleukin-6. Biochemistry 39:1942-1950. |
| 251. | Hammacher, A., Wijdenes, J., Hilton, DJ, Nicola, NA., Simpson, RJ, and Layton, JE (2000) Ligand-specific utilization of the extracellular membrane-proximal region of the gp130-related signalling receptors. Biochem. J. 345:25-32. |
| 252. | Reid, G.E., Simpson, R.J. and O'Hair, R.A.J. (1999) Probing the fragmentation of protonated glycine oligomers via multistage mass spectrometry and gas phase ion molecule reactions. Int. J. Mass Spectrom. 191:209-230. |
| 253. | Stacker, S.A., Stenvers, K., Caesar C., Vitali, A., Domagala, T., Nice, E., Roufaail, S., Simpson, R.J., Moritz, R., Karpanen, T., Alitalo, K., and Achen, M.G. (1999) Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. J. Biol. Chem. 274:32127-32136 |
| 254. | Simpson, R.J. Connelly, L.M., Eddes, J.S., Pereira, J.J., Moritz, R.L. and Reid, G.E. (2000) Proteomic analysis of the human colon carcinoma cell line (LIM 1215): Development of a membrane protein database. Electrophoresis. 21:1707-1732. |
| 255. | Tikoo, A., Shakri, R., Connolly, L.M., Hirokawa, Y., Shishido, T., Bowers, B., Ye, LH,, Kohama, K., Simpson, R.J., and Maruta, H. (2000) Treatment of RAS-induced cancers by the F-actin bundling drug MKT-077. Cancer J. (Boston MA) 6:162-168 |
| 256. | Cole, A.R., Ji, H., and Simpson, R.J. (2000) Proteomic analysis of colonic crypts from normal, MIN and p53-null mice: A comparison with colonic polypts. Electrophoresis 21:1772-1781. |
| 257. | Patterson, S., and Simpson, R.J. Conference call. (ICCP'99) Today's Life Science . 11(6):14. |
| 258. | Hill MM, Connolly LM, Simpson RJ, and James DE (2000) Differential protein phosphorylation in 3T3-L1 adipocytes in response to insulin versus PDGF. No evidence for a phosphatidylinositide 3-kinase independent pathway in insulin signalling. J. Biol. Chem. In press |
| 259. | Verhagen, A., Ehert, P.G., Silke, J., Pakusch, M., Connolly, L.M., Reid, G.E., Moritz, R.L., Simpson, R.J., and Vaux, D.L. (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to an antagonizing inhibitor of apoptosis (IAP) protein. Cell. 102:43-53. |
| 260. | Abola, E.E., Bairoch, A., Barker, W.C., Beck, S., Benson, D.A., Berman, H., Cameron, G., Cantor, C., Doubet, S., Hubbard, T.J.P., Jones, T.A., Kleywegt, G.J., Kolaskar, A.S., Van Kuit, A., Lesk, A.M., Mewes, H.W., Neuhaus, D., Pfeiffer, F., TenEcyck, L.F., Simpson, R.J., Stoesser, G., Sussman, J.L., Tateno, Y., Tsugita, A., Ulrich, E.L., Vliegenthart, J.F.G. (2000) Quality Control in Databanks for Molecular Biology BioEssays In press |
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